Don’t know if this will fix it, but it’s worth a look.
Client Access has a setting to automatically check the service level. You can disable it (Start > programs > IBM iSeries Access for Windows > IBM iSeries Access for Windows properties > Service – Select Never for when to check)
If it is enabled it may “periodically” check – which could be 4 to 5 weeks – and it may need admin rights, depending on how Windows is set up.
If that fixes it, let us know (in 4 or 5 weeks!…