In a former life we had a Zebra attached to our AS/400, when it was still called an AS/400. We just defined the Zebra as a character printer, such as an Epson 850. From that point on we treated it as a printer. In this config, it was not necessary to FTP the print file, which made our job a lot easier.
In my current life we have several DataMax bar code printers attached to our System i via TC