If they are windows folders, just right click and select delete. The same for Outlook folder, right click and select delete folder.
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First, did you create the folders or are they something you discovered while going through your system. If so, ensure that you do not delete something that belongs to a program.
On the deletion, two ways:
1. Click on it once, then press the Delete key.
2. Right click it, go down to Delete in the menu, click it.