evaluate the data
how often does the data change
how critical is it
how long must it be kept
are there any regulations involved
must a permanent copy be maintained
is off site storage going to be used
all data is not created equal, but if you don’t really care and just want to have a backup so you can say you have one then do daily differentials and a weekly full.
if you do care then you must do the work and research it. ck with someone from each interested data group. One business group manager may tell you that their transaction server is absolutely critical and each minute of down time cost thousands, so for that you want it clustered or real time replicated. Developement may tell you data changes a litlle each week but they need a copy saved forever. So for them daily incrimentals, weekly fulls which get overwritten each week and month but then end of month is saved for a year and the year end forever.
Do you get the idea? If you want to do it right, then you have to know the needs of that data and from there you can plan out what is best.
One more thing if you want to achive the potential throughput of those LTO drives then the backup application must support Multiplex.