Lotus Notes 8.x client is a single install, and it has two different configurations it can run in: Notes 8 (Standard Configuration) and Notes 8 (Basic Configuration).
As of Notes 8.0.2 and Notes 8.5, there is a Notes.ini parameter that can be used to control launching of Basic and Standard. Adding UseBasicNotes=1 to a Notes Standard install will launch Notes Basic instead. If the ini is not present or is set to UseBasicNotes=0, the Notes Standard client will run.
Alternatively you could use the windows api to query the process tree and determine …
if you can see two different executables, for example, notes2.exe/notesw.exe for the Standard Client and nlnotes.exe for Basic client.