If you’re wanting to encrypt data at rest, Crypto Complete from Linoma Software can encrypt data at the field level and backups. Using Crypto Complete, you don’t need to modify the source to encrypt the data and if you’re on V7R1, you don’t need to modify the source to decrypt it either. You can learn more about Crypto Complete here: http://www.linomasoftware.com/products/crypto
If you’re wanting to encrypt and automate file transfers from the iSeries (or other platforms), GoAnywhere Director from Linoma can do that for you. You can learn more about the GoAnywhere product suite here: http://www.goanywheremft.com.