just to share that there was a pc in office that had some problems and it was due to malware and using mcafee security suit, i could not find the virus. so i decided to to remove and install Microsoft Security Essentials and update it and it could fine the malware that was not able to be pickup by mcafee

I do lots and lots of computer cleanup. That is fixing computers after they have become infected. I have tested many many antivirus solutions for the enterprise as well as stand alone desktops.

I can tell you there is NO single good solution.

I use AVG antivirus on my main network. It was the best bang for the buck when I purchased.
I tested Vipre – it wanted computer restarted every other day, annoying.
Norton and Mcafee are big, use lots of computer resources, I do not use them and delete them off computers.

I have found that the biggest threat right now are user activated Trojans. These are becoming to be called Scareware. The problem with these is the user authorizes the install. NO anti virus or anti spam program will block these. One on the computer these things are very hard to stop.

Look at this article http://blogs.zdnet.com/security/?p=4297

I have found that protecting users from Malware is impossible. I have had people uninstall the antivirus/antispyware software, because it was blocking a web site. They uninstall the software then go to the site being blocked, then infect the computer! Then of course come crying to me, because the computer is no longer working correctly. (NO, I cannot block admin access on a persons personal computer!, wish I could!)

But if you have smart users, or wish to protect yourself I recommend the following

Use a security product that has web site protection, like AVG. Avast, even Norton or Mcafee

Use firefox for browsing.

Get the NO-script add-on and learn to use it. The NO script add-on is annoying. But it prevents scripts from running without your approval. You can even view the script before authorizing it. If you know a bit about programming, you can spot nasty scripts. Unfortunately teaching most people how to use it, is impossible.

Learn how to remove malware after you get it.