set the temp directory to F using the /t switch.
example – eseutil /d “f:\(store directory path) storename.edb” /tf:\temp.edb
Read the full article <a href=”http://support.microsoft.com/?id=192185″>here</a>
Actually, you can defrag any partition of your hard disk drive. There might be another problem with you partitioning of your hard disk drive. Make sure that each drive are partitioned equally and formatted properly for you to defrag and use the device.