Error 451 generally means that your server is being deferred. If you were to go to your mail server, and attempt to telnet into their mail server on port:
<pre>telnet example.com 25</pre>
You might get a “we are temporarily deferring you.” response, followed by a disconnect. That means that you are being deferred, either for sending that server too much mail in a short time frame, or because you are on a “black list” for one of many reasons. The easiest way to find out, is to check a couple black lists. My favorite is <a href=”http://www.senderbase.org/”>SenderBase</a>. If you are not on a black list, you are most likely being deferred for sending the destination mail server too many messages in an alloted time frame. That is usually resolved within a couple hours.