Vista Home Premium and Home Basic editions are not supported. The other editions are supported with:
V6R1M0 (5761-XE1 System i Access for Windows)
V5R4M0 (5722-XE1 iSeries Access for Windows) with service pack PTF SI25949 or later
PC5250 requires SI27741 or later
Click here to get the latest V5R4 service pack
The restrictions are in Information APAR II14239.
This can be found at the following website…