I am in the role that you want to be in. I have a degree in Business Management/ Information Systems. You need to focus on the business side of what ever company you want to work for. You need to have strong understanding on how the business works and on the processes the business uses to do day to day work. With that knowledge you can leverage your IT knowledge to provide solutions to solve specific business issues within the company. Remember to never try to introduce technology for technology’s sake. If your solution will not enhance sales, shorten cycle times, or increase production, it should not even be discussed.
When you are looking for a job, choose a profession you know well, or take the time to learn about the business you are looking into. In the interview, if you can discuss the specific business problems of the business and then showcase how your knowledge of IT will help solve those problems, you will have an advantage.
The job you are looking for is management level, so some prior experience may be needed. Hands on knowledge with the technical side will give you an advantage also. While you may not need to deal hands-on daily, the people you supervise will. If you need to take a non management position to gain experience, a systems analyst may be what you are looking for.