I have a Windows 2003 Active Directory domain. All "My Documents" folders are redirected to the fileserver. After I installed McAfee Antivirus Enterprise, a problem developed. Users (all runiing Windows XP) cannot save or open documents from the "My Documents" folder using Microsoft Office programs, such as Outlook. For example, when they try to save an email attachment from Outlook, they get an "Access Denied" message when they click on My Documents. They can, however, open or save them directly.
I read in a newsgroup that the solution for this problem was to make the users Power Users rather than Administrators locally. Oddly enough, that worked but now of course I have the problem that they can no longer install or run other applications.