Yes, but be careful:
i just got the Blackberry Curv. and while i was loading up the software on my laptop so that i could use Outlook with it, at some point it asked me if i wanted the changes i made on outlook to change the info that was on my phone. i naturally clicked yes to this. i then thought that i could install the same program on my home computer and click no to that very question. so that when i sync the phone to the 2nd computer it just puts the info that’s on the phone to the computer.
you could have your second computer make changes to your phone as well, however you will need to get into the habit of syncing the phone when you make the change on ether computer. because if you don’t, and you make a change on both computer without syncing in between, the one you sync with second will overwrite any changes made by the first compute to your phone.