Without the remote agent, If a mail file is being backed up at the same time that the router tries to deposit a piece of mail into the file, the database can become corrupted. The effect is only on the database in production on the server; it does not effect the file that is on the backup tape. AFAIK, the remote agent only accomplishes one thing (and, in our experience, often doesn’t even do that). That is, it temporarily marks the file being backed up as “busy” so that the router doesn’t access it at the same time. As long as your backups are good (able to perform a clean restore), you should have no problems. With the exception of Domino 8.x with DAOS running, everything you need to restore a user’s mailfile is in the Domino directory (e.g., /Lotus/Domino/data). HTH.