It is possible by using “Backup Schedule Wizard” in Windows Server 2008 R2 (as you mentioned) to schedule backups which may run automatically once / more. It is also possible to create scheduled backups using Wbadmin enable backup command.
Remember, Windows Server Backup is a disk-to-disk backup solution. And keep in mind that Windows Server Backup has 4 ways…..
Backup management console / wbadmin.msc (i.e. simply a GUI feature)
- Command line tool / wbadmin (which I mentioned)
- Backup service / wbengine
- Cmdlets (Powershell)
See here for Wbadmin enable backup.